Kevin Brown Chandler, Ph.D.

Kevin Chandler is a researcher in the Translational Glycobiology Institute at Florida International University (TGIF). He is a Harvard ProTG K12 Program Scholar under the mentorship of TGIF founders
Dr. Robert Sackstein, Dean of the College of Medicine, and Charles Dimitroff, Executive Associate Dean for Research.

Education

Ph.D. in Biochemistry and Molecular Biology, Georgetown University, Washington, D.C.
B.S. in Biochemistry and Molecular Biophysics, University of Arizona, Tucson, Arizona

Selected Publications

 View the full list of Kevin Chandler's publications.

1. Chandler KB, Alamoud KA, Stahl VL, Nguyen BC, Kartha VK, Bais MV, Nomoto K, Owa T, Monti S, Kukuruzinska MA, Costello CE. β-Catenin/CBP inhibition alters epidermal growth factor receptor fucosylation status in oral squamous cell carcinoma. Mol Omics. 2020 Jun 1;16(3):195-209. doi: 10.1039/d0mo00009d. Epub 2020 Mar 23. PMID: 32203567; PMCID: PMC7299767.
2. Chandler KB, Leon DR, Kuang J, Meyer RD, Rahimi N, Costello CE. N-Glycosylation regulates ligand-dependent activation and signaling of vascular endothelial growth factor receptor 2 (VEGFR2). J Biol Chem. 2019 Aug 30;294(35):13117-13130. doi: 10.1074/jbc.RA119.008643. Epub 2019 Jul 15. PMID: 31308178; PMCID: PMC6721943.
3. Chandler KB, Costello CE, Rahimi N. Glycosylation in the Tumor Microenvironment: Implications for Tumor Angiogenesis and Metastasis. Cells. 2019 Jun 5;8(6). doi: 10.3390/cells8060544. Review. PMID: 31195728; PMCID: PMC6627046.
4. Chandler KB, Mehta N, Leon DR, Suscovich TJ, Alter G, Costello CE. Multi-isotype Glycoproteomic Characterization of Serum Antibody Heavy Chains Reveals Isotype- and Subclass-Specific N-Glycosylation Profiles. Mol Cell Proteomics. 2019 Apr;18(4):686-703. doi: 10.1074/mcp.RA118.001185. Epub 2019 Jan 18. PMID: 30659065; PMCID: PMC6442369.
5. Chandler KB, Leon DR, Meyer RD, Rahimi N, Costello CE. Site-Specific N-Glycosylation of Endothelial Cell Receptor Tyrosine Kinase VEGFR-2. J Proteome Res. 2017 Feb 3;16(2):677-688. doi: 10.1021/acs.jproteome.6b00738. Epub 2016 Dec 29. PMID: 27966990; PMCID: PMC5291786.