David Marciano’s research is focused on investigating mechanisms of extracellular vesicle signaling in the vasculature and their application as therapeutics, biomarkers, and molecular tools.
See research publications and more on FIU Discovery.
Contact Us
For information about our lab or undergraduate research opportunities, please contact us at dmarcian@fiu.edu.
About the Lab
The Marciano Lab investigates how mechanical and oxidative stress reprogram endothelial cell signaling, epigenetic remodeling, and extracellular vesicle biology in pulmonary arterial hypertension and other cardiopulmonary vascular diseases. Using advanced endothelial shear stress systems, multi-omics technologies, extracellular vesicle profiling, and translational patient studies, the lab investigates how abnormal vascular environments drive endothelial dysfunction and vascular remodeling. The laboratory is currently supported by funding from the NIH National Heart, Lung, and Blood Institute, the American Heart Association, and FIU/Baptist Health collaborations focused on vascular biology and extracellular vesicle biomarkers for early lung cancer detection.
Lab equipment
- Microfluidic platform that allows endothelial cells to be exposed to physiologically relevant laminar flow and oxygen conditions that mimic the pulmonary vascular environment in health and disease.
Lab Members
Amber Eliason
Lab Manager
Santiago Moreno-Caceres
Ph.D. Student
Donate
Interested in supporting our research or scholars?
Please contact:
Naomi Nixon
Associate Dean for Development
Phone: 305-348-9038
Email: nnixon@fiu.edu