Madepalli Lakshmana has more than twenty years of experience in basic and translational research of neurodegenerative disorders, particularly Alzheimer’s disease.
Lakshmana developed several biological assays on proteins such as sAPPα (neuroprotection), HDAC2 (epigenetics), and TFEB (autophagy) and has identified several hits which are at various stages of development.
See research publications and more on FIU Discovery.
Contact Us
For information about our lab or undergraduate research opportunities, please contact us at mlakshma@fiu.edu.
The Lakshmana lab utilizes the following methods and models:
- Transgenic mice, temporal and cell-type-specific knockout mice
- Transmission electron microscopy
- Primary neuronal cultures
- Proteomics
- High-throughput and high-content screening
- ELISA, immunoblotting, and immunohistochemistry
- Induced pluripotent stem cell-derived neurons
- Human brain tissues from Alzheimer’s and ALS patients
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Interested in supporting our research or scholars?
Please contact:
Naomi Nixon
Associate Dean for Development
Phone: 305-348-9038
Email: nnixon@fiu.edu