Daniel Chaparro leads research efforts focused on the development of living allogeneic heart valve transplants through the integration of biomedical engineering principles and translational science in the Kalfa Lab. His work centers on the design and optimization of bioreactor-based systems for the storage, rehabilitation, and functional preservation of valvular tissues, with the ultimate goal of producing living valvular allografts capable of treating congenital heart defects and reducing the need for repeated surgical interventions as pediatric patients grow. He mentors undergraduate, graduate and junior engineering staff in experimental rigor, documentation practices, and regulatory and translational research principles.
In this role, he leads the development of tissue-based bioreactor platforms in support of translational and clinical research objectives, translates clinical and user needs into engineering requirements, specifications, and performance criteria while maintaining design documentation aligned with design control and regulatory expectations.
Chaparro also plans and executes experimental and engineering runs to analyze quantitative data, and report outcomes to multidisciplinary research and clinical teams. He coordinates with clinicians, surgeons, suppliers and internal collaborators to assess feasibility, safety, and performance of tissue products and bioprocesses.
Areas of Expertise
- Cardiovascular biomechanics
- Translational research
- Medical device prototyping
Research Interests
- Cardiac and valvular congenital and acquired pathologies
Committees & Professional Organizations
- Member, Young Professionals Network of the Heart Valve Society Board
Education
- Ph.D., Biomedical Engineering, Florida International University 2025
- MS, Biomedical Engineering, Florida International University 2023
- BS, Biomedical Engineering, Florida International University 2018