Publications

  1. Sgoutas DS, Abbott KL. “Cyclosporine does not interfere in total and high density lipoprotein cholesterol measurement with use of enzymatic cholesterol assays” Clinical Chemistry, 35(11):2251 (1989).[PMID: 2582627]
  2. Hunter BD, Bandea C, Swan D, Abbott K, Varma VA. “Mutations in the p53 gene in human astrocytomas: detection by single-strand conformation polymorphism analysis and direct DNA sequencing” Pathol., 6(4) 442-5 (1993).[PMID:8415589] Hunter S, Gramlich T, Abbott K, Varma V. “Y chromosome loss in esophageal carcinoma: an in situ hybridization study” Genes Chromosomes Cancer, 8(3):172-7 (1993).[PMID:7509625]
  3. Varma VA, Cerjan CM, Abbott KL, Hunter SB. “Non-isotopic in situ hybridization method for mitochondria in oncocytes” Histochem. Cytochem., 42(2):273-6 (1994).[PMID:8288868]
  4. Hunter SB, Abbott K, Varma VA, Olsen JJ, Barnett DW, James CD. “Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue” Neuropatho.l Exp. Neurol., 54(1)57-64 (1995).[PMID:7815080]
  5. Boss V, Abbott KL, Wang XF, Pavlath GK, Murphy TJ. “The cyclosporine A-sensitive nuclear factor of activated T cells (NFAT) proteins are expressed in vascular smooth muscle cells. Differential localization of NFAT isoforms and induction of NFAT-mediated transcription by phospholipase C-coupled cell surface receptors” Biol. Chem., 273(31):19664-71 (1998).[PMID:9677394]
  6. Abbott KL, Friday BB, Thaloor D, Murphy TJ, Pavlath GK. “Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells” Biol. Cell. 9(10):2905-16 (1998).[PMID:9763451
  7. Abbott KL, Robida AM, Davis ME, Pavlath GK, Camden JM, Turner JT, Murphy TJ. “Differential regulation of vascular smooth muscle nuclear factor kappa-B by G alpha q-coupled and cytokine receptors” Mol. Cell Cardiol, 32(3):391-403 (2000).[PMID:10731439]
  8. Minneman KP, Lee D, Zhong H, Berts A, Abbott KL, Murphy TJ. “Transcriptional responses to growth factor and G protein-coupled receptors in PC12 cells: comparison of alpha(1)-adrenergic receptor subtypes” Neurochem, 74(6):2392-2400 (2000).[PMID:10820200]
  9. Abbott KL, Loss JR 2nd, Robida AM, Murphy TJ. “Evidence that G alpha(q)-coupled receptor-induced interleukin-6 mRNA in vascular smooth muscle cells involves the nuclear factor of activated T cells” Pharmacol, 58(5):946-53 (2000).[PMID:11040041]
  10. Murphy TJ, Pavlath GK, Wang X, Boss V, Abbott KL, Robida AM, Nichols J, Xu K, Ellington ML, Loss JR 2nd (2002). “Retroviral vectors applied to gene regulation studies” Methods Enzymol, 345:539-51.[PMID:11665637]
  11. Nguyen BD, Abbott KL, Potempa K, Kobor MS, Archambault J, Greenblatt J, Legault P, Omichinski JG.” NMR structure of a complex containing the TFIIF subunit RAP74 and the RNAPII CTD phosphatase FCP1” Natl. Acad. Sci. USA, 100 (10):5688-93(2003).[PMID:12732728]
  12. Abbott KL, Archambault J, Xiao H, Nguyen BD, Roeder RG, Greenblatt J, Omichinski J, Legault P. “Interactions of the HIV-1 Tat and RAP74 proteins with the RNA polymerase II CTD phosphatase FCP1” Biochemistry ,44:2716-31(2005).[PMID:15723517]
  13. Abbott KL, Renfrow M, Chalmers MJ, Nguyen BD, Marshall AG, Legault P, Omichinski J. “Enhanced binding of RNAP II CTD Phosphatase FCP1 to RAP74 following CK2 phosphorylation” Biochemistry, 44:2732-45 (2005).[PMID:15723518]
  14. Lee I, Guo HB, Kamar M, Abbott K, Troupe K, Lee JK, Alvarez-Manilla G, Pierce M. “N-acetylglucosaminyltransferase VB expression enhances beta 1 integrin-dependent PC12 neurite outgrowth on laminin and collagen” Neurochem, 97(4) 947-56 (2006).[PMID:16606368]
  15. Abbott KL*, Troupe K, Lee I, Pierce M. “Integrin-dependent neuroblastoma cell adhesion and migration on laminin is regulated by expression levels of two enzymes in the O-mannosyl-linked glycosylation pathway, PomGnT1 and GnT-Vb” Exp Cell Res. 312(15):2837-50 (2006).[PMID:16857188]
  16. Abbott KL*, Aoki K, Lim J, Perlman M, Johnson R, O’Regan RM, Wells L, Tiemeyer M, Pierce M (2008) Targeted glycoproteomic identification of biomarkers for human breast carcinoma. Proteome Res. 7: 1470-1480. [PMID: 18271524]
  17. Abbott KL*, Nairn AV, Hall EM, Horton, MB, Walker D, McDonald JF, Moremen KW, Dinulescu DM, Pierce M (2008) Focused glycomic analysis for the N-linked glycan pathway in ovarian cancer. Proteomics 8: 3210-3220 (Selected for journal cover). [PMID: 18690643]
  18. Abbott KL*, Matthews RT, Pierce M (2008) Receptor tyrosine phosphatase (RPTPb) activity and signaling are attenuated by glycosylation and subsequent cell surface galectin-1 binding. Biol. Chem. 283: 33026-33035.  [PMCID: PMC2586282]
  19. Yang A, Abbott KL, Desjardins A, DiLello P, Omichinski JG, Legault P (2009) NMR structure of a complex formed by the carboxyl-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 phosphatase. Biochemistry 48: 1964-1974. [PMID: 19215094]
  20. Abbott KL*, Lim J, Wells L, Benigno BB, McDonald JF, Pierce M (2010) Identification of candidate biomarkers with cancer-specific glycosylation in the tissue and serum of endometrioid ovarian cancer patients by glycoproteomic analysis. Proteomics 10: 470-481. [PMID: 19953551]
  21. Abbott KL (2010) Glycomic analysis of ovarian cancer: past, present, and future. Cancer Biomarkers. 8 (4-5):273-80. [PMID: 22045358].
  22. Abbott KL, Pierce JM (2010) Lectin-based glycoproteomic techniques for the enrichment and identification of potential biomarkers. Methods Enzymol 480:461-76. [PMID:20816222]
  23. Dengaj D, Abbott KL, Mookerjee A, Zhao A, Kirby PS, Sandaltzopoulos R, Powell DJ, Siegel DL, Wolf C, and Scholler N (2011) Mannose receptor engagement by mesothelin GPI anchor polarizes tumor associated macrophages and is blocked by a recombinant antibody directed against mannose receptor domain 4. PLoS One. 6 (12): e28386. [PMID:22163010][PMCID:3232216]
  24. Zhao P, Nairn A, Hester S, Moremen K, O’Regan R, Oprea G, Wells L, Pierce M, and Abbott KL* (2012) Proteomic identification of glycosylphosphatidylinositol anchor-dependent membrane proteins elevated in breast carcinoma. J. Biol. Chem. 287(30):25230-40.[PMID: 22654114] [PMCID:3408190]
  25. Dolezal S, Hester S, Kirby PS, Nairn A, Pierce M, Abbott KL*. (2014) “Elevated levels of glycosylphosphatidylinositol (GPI) anchored proteins in plasma from human cancers detected by septicum alpha toxin”. Cancer Biomark. 14(1):55-62. [PMID 24643042] [PMC 4157464]
  26. Guo H, Abbott KL.*( 2015)“Functional impact of tumor-specific N-linked glycan changes in breast and ovarian cancers”. Adv. Cancer Res. 126:281-303[PMID 25727151]
  27. Allam H, Aoki K, McDonald JF, MacIntosh SG, Tiemeyer M, Abbott KL *(2015) “Glycomic analysis of membrane glycoproteins with bisecting glycosylation from ovarian cancer tissues reveal novel structures and functions.” J Proteome Res. 14(1):434-46.[PMID 25437919] [PMC 4286206] 
  28. Allam H, Johnson BP, Zhang, Lu Z, Cannon MJ, Abbott KL (2017) The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer. J. Biol. Chem. 292(39): 16351-16359 [PMID 28842505]
  29. Lu Z, Kamat K, Johnson BP, Yin CC, Scholler N, and Abbott KL (2019) Generation of a Fully Human scFv that binds Tumor-Specific Glycoforms. Sci. Rep. 9(1):5101 [PMID 30911061]
  30. Rikitake M, Matsuda A, Murata D, Dejima K, Nomura KH, Abbott KL, Mitani S, Nomura K (2020) Analysis of GPI-anchored proteins involved in germline stem cell proliferation in the Caenorhabditis elegans germline stem cell niche. J. Biochem 2020 Dec 26;168(6):589-602 [PMID 32844210]
  31. Murali P, Johnson BP, Lu Z, Climer L, Scott, DA, Foulquier F, Oprea-Ilies G, Lupashin V, Drake RR, and Abbott KL (2020) Novel Role for the Golgi Membrane Protein TMEM165 in Control of Migration and Invasion for Breast Carcinoma. 2020; 11: 2747-2762. Retrieved from https://www.oncotarget.com/article/27668/ (Cover Oncotarget)