Ng, Hooi Hooi, PhD
Office: AHC1 320A
Dr. Ng is an American Heart Association (AHA) postdoctoral fellow. She earned her doctoral degree in vascular physiology at The University of Melbourne, Australia in 2017, examining the role of a naturally occurring peptide hormone, relaxin, in diseased blood vessels. Her main research interests involve defining the cellular and molecular mechanisms in the initiation and progression of hyperglycemia-induced vascular calcification, and examining the therapeutic potential of relaxin-based therapies for the treatment of vascular diseases, in particular those associated with atherosclerosis and diabetes.
Her AHA-funded research aims to investigate the therapeutic potential of a small molecule relaxin mimetic for the treatment of diabetes-induced vascular calcification. Diabetes is a known risk factor for vascular calcification, the accumulation of calcium mineral in the arterial wall. It is now apparent that calcification of the vessels is the most significant predictor of coronary artery disease and heart failure. To date, there are no approved pharmacotherapies for the treatment of vascular calcification. The outcomes of her project will provide new mechanistic insights into the potential role of a small molecule to arrest the progression of this process in diabetes.
Complete List of Published Work in My Bibliography: