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Atluri, Venkata Subba Rao

Title: Assistant Professor

Office: AHC1 417B

Phone: 305-348-6020

Email: vatluri@fiu.edu

Curriculum Vitae

Department(s): Immunology




Dr. Atluri has obtained his Ph.D. from Postgraduate Institute of Medical Education and Research, Chandigarh, India in 2009. He moved to Florida International University (FIU), Miami, FL, USA to pursue his post-doctoral research and subsequently appointed as Assistant Professor in the Department of Immunology at FIU. His current research is focused on neuropathogenic mechanisms of HIV infection and drugs of abuse; and epigenetic regulation of synaptic plasticity in HIV exposed neuronal cells. For the first time, Dr. Atluri has reported the dysregulation of synaptic plasticity genes and spine density in HIV exposed neuronal cells and reported the usefulness of vorinostat as a therapeutic agent to inhibit the negative regulatory effects on synaptic plasticity in HIV infection. His group has developed magnetic nanoparticle based drug delivery system to deliver anti-HIV and latency breaking agents across the blood brain barrier for sustained delivery for longer duration. In his research career, he has published many research papers and abstracts in peer-reviewed scientific journals. He has been serving as an Editorial Board member of Scientific Reports, Frontiers in Virology, AIDS and Behavior, International Journal of Nanomedicine, Neuropsychiatric disease and treatment, HIV/AIDS-Research and Palliative Care etc.; and reviewer of many peer-reviewed scientific journals. He is recipient of gold medals for being outstanding undergraduate and college topper for the year 2000 from V.K.R. College, Nagarjuna University, India. He has also received many travel awards to attend national and international scientific meetings.

Education and Training

  • Post-doctoral Research Associate at Florida International University, Miami, FL.
  • Ph.D. from Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Masters (M.Sc.) in Medical Microbiology from Manipal University, Manipal, India.
  • Bachelors (B.Sc.) in Microbiology, Biochemistry and Nutrition from Nagarjuna University, India.

Specialties

  • Immunology and Neuro-AIDS
  • Medical Microbiology and Infectious Diseases
  • Molecular Biology

Recent Publications

  • Venkata S R Atluri, Rahul Dev Jayant, Sudheesh Pilakka Kanthikeel, Gabriella Garcia, Samikkannu Thangavel, Adriana Yndart, Ajeet Kaushik and Madhavan Nair. 2016. Development of Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Magnetic Nanoformulation for Regulation of Synaptic Plasticity in HIV-1 Infection. International Journal of Nanomedicine. In Press.
  • Venkata S Atluri, Sudheesh Pilakka-Kanthikeel, Gabriella Garcia, Rahul Dev Jayant, Vidya Sagar, Samikkannu Thangavel, Adriana Yndart, Madhavan Nair. 2016. Effect of Cocaine on HIV infection and Inflammasome Gene Expression Profile in HIV Infected Macrophages. Scientific Reports, 6: 27864. doi: 10.1038/srep27864.
  • Marisela Agudelo, Gloria Figueroa, Adriana Yndart, Karla Munoz, Venkata Atluri, Samikkannu Thangavel, Madhavan P. Nair. 2016. Profile of Class I Histone Deacetylases (HDAC) by Human Dendritic Cells after Alcohol Consumption and in vitro Alcohol Treatment and their Implication in Oxidative Stress: Role of HDAC Inhibitors Trichostatin A and Mocetinostat. PLoS ONE, 11(6): e0156421. doi:10.1371/journal.pone.0156421.
  • Atluri, V.S.R*., Sagar, V*., Pilakka-Kanthikeel, S., & Nair, M. 2016. Magnetic nanotherapeutics for synaptic plasticity dysregulations during neuroAIDS and drug abuse. Molecular Brain, 9:57. DOI: 10.1186/s13041-016-0236-0. *Equal First Author Contribution.
  • Rahul Dev Jayant, Daniela Sosa, Ajeet Kaushik, Venkata Atluri, Arti Vashist, Asahi Tomitaka, Madhavan Nair. 2016. Current status of non-viral gene therapy for CNS disoders. Expert Opinion on Drug Delivery. DOI:10.1080/17425247.2016.1188802.
  • Ajeet Kaushik, Rahul D. Jayant, Roozbeh Nikkhah-Moshaie, Vinay Bhardwaj, Upal Roy, Zaohua Huang, Ariel Ruiz, Adriana Yndart, Venkata Atluri, Nazira El-Hage, Kamel Khalili, Madhavan Nair. 2016. Magnetically guided central nervous system delivery and toxicity evaluation of magneto-electric nanocarriers. Scientific Reports. 6:25309; DOI: 10.1038/srep25309.
  • Venkata Subba Rao Atluri. 2016. Editorial:  HIV and illicit drugs of abuse. Frontiers in Microbiology. 7: 221. doi: 10.3389/fmicb.2016.00221.
  • Venkata Subba Rao Atluri*, Kesava Rao Venkata Kurapati*, Samikkannu Thangavel, Gabriella Garcia, Madhavan Nair. 2016. Natural Products as Anti-HIV Agents and Role in HIV-Associated Neurocognitive Disorders (HAND): A Brief Overview. Frontiers in Microbiology, 6: 01444. doi:  10.3389/fmicb.2015.01444. *Equal First Author Contribution.
  • Marisela Agudelo.,  Gloria Figueroa.,  Adriana Yndart.,  Gianna Casteleiro.,  Karla Muñoz.,  Thangavel Samikkannu., Venkata Subba Rao Atluri and  Madhavan P. Nair. 2015. Alcohol and cannabinoids differentially affect HIV infection and function of human monocyte-derived dendritic cells (MDDC). Frontiers in Microbiology, 6:1452. doi: 10.3389/fmicb.2015.01452.
  • Venkata Atluri, Melissa Hidalgo, Samikkannu Thangavel, Kesava Rao Kurapati, Madhavan Nair. 2015. Synaptic plasticity and cognitive disorders in neurotropic viral infections. Neural Plasticity, Article ID 138979, http://dx.doi.org/10.1155/2015/138979.
  • Upal Roy, Hong Ding, Sudheesh Pilakka Kanthikeel, Andrea Raymond, Venkata Atluri, Adriana Yndart, Madhavan Nair. 2015. Preparation and characterization of anti-HIV nanodrug targeted to microfold cell of gut-associated lymphoid tissue. International Journal of Nanomedicine, 10: 5819-5835. PMID: 26425084.
  • Venkateswara Reddy Gogulamudi, Mohan Lal Dubey, Deepak Kaul, Venkata Subba Rao Atluri, Rakesh Sehgal. 2015. Downregulation of host tryptophan-aspartate containing coat (TACO) gene restricts the entry and survival of Leishmania donovani in human macrophage model. Frontiers in Microbiology, Front. Microbiol. 6:946. doi: 10.3389/fmicb.2015.00946
  • Upal Roy, Venkata Atluri, Marisela Agudelo, Madhavan Nair. 2015. DJ1 Expression Downregulates in Neuroblastoma Cells (SK-N-MC) Chronically Exposed to HIV-1 and Cocaine. Frontiers in Microbiology, 6:749. doi: 10.3389/fmicb.2015.00749. PMID: 26284039
  • Adriana Yndart, Ajeet Kaushik, Marisela Agudelo, Andrea Raymond, Venkata Atluri, Shailendra Saxena, and Mahdavan Nair. 2015. Investigation of Neuropathogenesis in HIV-1 Clade B and C Infection Associated with IL-33 and ST2 Regulation. ACS Chemical Neuroscience. 2015 Sep 16;6(9):1600-12. PMID: 26110635.
  • Samikkannu T, Ranjith D, Rao KVK, Atluri VSR, Pimentel E, El-Hage N, Nair MPN. 2015. HIV-1 gp120 and morphine induced oxidative stress: role in cell cycle regulation. Front. Microbiol. 6:614. doi: 10.3389/fmicb.2015.00614. PMID: 26157430
  • Sagar Vidya, Pilakka-Kanthikeel S, Atluri VSR, Ding H, Priestap H, Nair M.P. 2015. Therapeutical Neurotargeting via Magnetic Nanocarrier: Implications to Opiate-Induced Neuropathogenesis and NeuroAIDS. Journal of Biomedical Nanotechnology, 11: 1722-1733. PMID: 26502636
  • Samikkannu Thangavel, Kesava Rao Kurapati, Abdul Ajees Abdul Salam, Venkata Atluri, Elena Kaftanovskaya, Marisela Agudelo, Suray Perez, Andrea Raymond, Hong Ding, Madhavan Nair. 2015. HIV Subtypes B and C gp120 and Methamphetamine Interaction: Role of Dopaminergic System Implicates Differential Neuronal Toxicity. Scientific Reports., 5. Article number: 11130 doi:10.1038/srep11130. PMID: 26057350.
  • Venkata Atluri, Melissa Hidalgo, Samikkannu Thangavel, Kesava Rao Kurapati, Rahul Jayant, Vidya Sagar, Madhavan Nair. 2015. Effect of human immunodeficiency virus on blood-brain barrier integrity and function: an update. Frontiers in Cellular Neuroscience, 9:212. doi: 10.3389/fncel.2015.00212. PMID: 26113810.
  • Sudheesh PK, Andria Raymond, Venkata Subba Rao Atluri; Vidya Sagar, Shailendra Saxena, Patricia Diaz, Semithe Chevelon, Michael Concepcion, Madhavan Nair. 2015. Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1)-facilitated HIV restriction in astrocytes is regulated by miRNA-181a. Journal of Neuroinflammation 2015, 12:66. PMID: 25890101.
  • Venkata Atluri*, Melissa Hidalgo*, Madhavan Nair. 2015. Drugs of abuse in HIV infection and neurotoxicity. Frontiers in Microbiology, 6: 217. PMID: 25852673. *Equal First Author Contribution.
  • Rahul Dev Jayant, Venkata Atluri, Marisela Agudelo, Vidya Sagar, Ajeet Kaushik, Madhavan Nair. 2015. Sustained Release NanoART Formulation for the Treatment of NeuroAIDS. International Journal of Nanomedicine, 10: 1077-1093. PMID: 25709433.
  • Ajeet Kaushik, Adriana Yndrt, Rahul Dev Jayant, Vidya Sagar, Venkata Atluri, Shekhar Bhansali, Madhavan Nair. 2015. Electrochemical sensing method for point-of-care cortisol detection in HIV infected patients. International Journal of Nanomedicine. International Journal of Nanomedicine, 10: 677-685. PMID: 25632229.
  • Samikkannu Thangavel, Venkata Atluri, Adriana Yndart, Kesava Rao Venkata Kurapati, Carmen T Mulet, Rahul Dev Jayant, Madhavan Nair. 2014. HIV-1 Subtypes B and C Tat Differentially Impact Synaptic Plasticity Expression and Implicates HIV-Associated Neurocognitive Disorder. Current HIV Research, 12(6), 397-405. PMID: 25613138.
  • Kesava Rao Venkata Kurapati, Thangavel Samikkannu, Venkata Subba Rao Atluri, Elena Kaftanovskaya, Adriana Yndart, Madhavan P. N. Nair. 2014. β- Amyloid1-42, HIV-1Ba-L (clade B) Infection and Drugs of Abuse Induced Degeneration in Human Neuronal Cells and Protective Effects of Ashwagandha (Withania somnifera) and its constituent Withanolide A. PLoS ONE. PLoS ONE 9(11): e112818. doi:10.1371/journal.pone.0112818. PMID: 25415340.
  • Venkata Subba Rao Atluri, Kesava Rao Venkata Kurapati, Thangavel Samikkannu and Madhavan P.N. Nair. 2014. Biomarkers of HIV Associated Neurocognitive Disorders. JSM Biomarkers; 1(1): 1002.
  • Venkata Subba Rao Atluri, Venkateswara Reddy Gogulamudi, Pratibha Singhi, Niranjan Khandelwal, Lakshmana Swamy Parasa, Nancy Malla. 2014. Pediatric neurocysticercosis: usefulness of antibody response in cysticidal treatment follow-up. BioMed Research International. Volume 2014, Article ID # 904046. http://dx.doi.org/10.1155/2014/904046. PMID: 25215297
  • Venkata Subba Rao Atluri, Sudheesh Pilakka-Kanthikeel, Samikkannu Thangavel, Vidya Sagar, Kesava Rao Venkata Kurapati, Shailendra K Saxena, Adriana Yndart, Andrea Raymond, Hong Ding, Oscar Hernandez, Madhavan P.N. Nair. 2014. Vorinostat positively regulates synaptic plasticity genes expression and spine density in HIV infected neurons: Role of nicotine in progression of HIV-associated neurocognitive disorders. Molecular Brain. 7:37 (15 May 2014). PMID: 24886748.
  • Samikkannu T, Rao KV, Pilakka Kanthikeel S, Venkata SR Atluri, Agudelo M, Roy U, Nair MP. 2014. Immunoneuropathogenesis of HIV-1 clades B and C: Role of redox expression and thiol modification. Free Radic Biol Med. 2014; 69:136-44. PMID: 24480751.
  • Hong Ding, Vidya Sagar, Marisela Agudelo, Sudheesh Pilakka-Kanthikeel, Venkata Subba Rao Atluri, Andrea Raymond, Thangavel Samikkannu and Madhavan P Nair. 2014. Enhanced blood brain barrier transmigration using a novel transferrin embedded fluorescent magneto-liposome nanoformulation. Nanotechnology 25; 055101, doi:10.1088/0957-4484/25/5/055101. PMID: 24406534.
  • Venkata Subba Rao Atluri, Thangavel Samikkannu, Kesava Rao Venkata Kurapati, Madhavan PN Nair. 2014. Commentary of Drugs of Abuse and HIV Infection in South Florida, USA. Austin Journal of Drug Abuse and Addiction. 05/2014; 1(1):3.
  • Kurapati, V.K.R, Samikkannu T, Atluri, V.S.R, Nair, M.P.N. 2014. Cell Cycle Checkpoints and Pathogenesis of HIV-1 infection: A Brief Overview. Journal of basic and clinical physiology and pharmacology. July 19, 2014, DOI: 10.1515/jbcpp-2014-0018. PMID: 25046311.
  • Rakesh Guduru, Ping Liang, Carolyn D. Runowicz, Madhavan Nair, Venkata Atluri, Sakhrat Khizroev. 2013. Magneto-electric Nanoparticles to Enable Field-controlled High-Specificity Drug Delivery to Eradicate Ovarian Cancer Cells. Nature Scientific Reports. 2013/10/16/online. doi: 10.1038/srep02953
  • Kurapati KRV, Atluri VSR, Samikkannu T, Nair MPN. 2013. Ashwagandha (Withania somnifera) Reverses β-Amyloid1-42 Induced Toxicity in Human Neuronal Cells: Implications in HIV-Associated Neurocognitive Disorders (HAND). PLoS ONE 8(10): e77624. doi:10.1371/journal.pone.0077624.
  • Venkata Subba Rao Atluri, Sudheesh P. Kanthikeel, Pichili VB Reddy, Adriana Yndart, Madhavan Nair. 2013. Human Synaptic Plasticity gene expression profile and dendritic spine density changes in HIV-infected human neuronal cells: Role in HIV-associated neurocognitive disorders. PLoS ONE 8(4): e61399. doi:10.1371/journal.pone.0061399.
  • Sudheesh PK; Venkata Subba Rao Atluri; Vidya Sagar, Madhavan Nair. 2013. Targeted brain derived neurotropic factors (BDNF) delivery across the blood-brain barrier for neuro-protection using magnetic nano carriers: an in-vitro study. PLoS ONE 8(4): e62241. doi:10.1371/journal.pone.0062241.
  • Pichili Vijaya Bhaskar Reddy, Marisela Agudelo, Venkata SR Atluri, and Madhavan P Nair. 2012. Inhibition of Nuclear factor erythroid 2-related factor-2 (Nrf2) exacerbates the HIV-1 gp120-induced oxidative and inflammatory Response: Role in HIV associated neurocognitive disorder. Neurochemical Research, 37(8): 1697-706.
  • Rita Mukhopadhyay., Goutam Mandal., Venkata Subba Rao Atluri., Katherine Figarella., Nestor L. Uzcategui., Yao Zhou., Eric Beitz., A. Abdul Ajees and Hiranmoy Bhattacharjee. 2011. The role of alanine 163 in solute permeability of Leishmania major aquaglyceroporin LmAQP1. Molecular and Biochemical Parasitology, 175(1): 83-90.
  • Atluri, V.S.R., Singhi, P., Khandelwal, N., Malla, N. 2011. 2D-PAGE analysis of Taenia solium metacestode 10-30 kDa antigens for the serodiagnosis of neurocysticercosis in children. Acta Tropica, 2011; 118(2): 165-169.
  • Sehgal R., Gogulamudi V. Reddy., Jaco J. Verweij., Atluri V. Subba Rao. 2010. Prevalence of intestinal parasitic infections among school children and pregnant women in a low socio-economic area, Chandigarh, North India. Reviews in Infection, 1(2): 100-103.
  • Lakshmana swamy Parasa., Cyril Arun kumar., Sirisha Para., Venkata Subba Rao Atluri, K. Santhisree, P. Raja Kumar and C. Rattiah Setty. 2010. Epidemiological survey of methicillin resistant Staphylococcus aureus in the community and hospital, gannavaram, andhra pradesh, south India, Reviews in Infection, 1(2): 117-123.
  • Atluri, V.S.R., Singhi, P., Khandelwal, N., Malla, N. 2009. Evaluation of excretory secretory and 10-30 kDa antigens of T. solium Cysticerci by EITB assay for the diagnosis of neurocysticercosis. Parasite Immunology, 31(3): 151-5.
  • Atluri,V.S.R., Singhi, P., Khandelwal, N., Malla, N. 2009. Neurocysticercosis immunodiagnosis using Taenia solium Cysticerci crude soluble extract, excretory secretory and lower molecular mass antigens in serum and urine samples of Indian children. Acta Trop., 110(1):22-7.