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Nikkhah Moshaie, Roozbeh

Title: Postdoctoral Associate

Office: AHC1- 415

Phone: 305-348-4978

Email: rnikkhah@fiu.edu

Department(s): Immunology

Dr. Roozbeh Nikkhah-Moshaie received his Ph.D. (2016) in Materials Science and Engineering from Department of Mechanical and Materials Engineering, College of Engineering and Computing,
Florida International University (FIU), Miami, FL, USA. He then joined Center for Personalized Nanomedicine at the Institute of NeuroImmune Pharmacology of the Department of Immunology at FIU Herbert Wertheim College of Medicine, as a Post-Doctoral Research Associate. He is an experimental materials scientist with focus on nanotechnology, magnetism, nanomedicine, microscopy, imaging, and analytical techniques. His research includes design, development, and fabrication of novel nanocarriers for noninvasive targeted drug delivery and controlled on-demand release in brain cells infected with Neuro-AIDS. In addition, he conducts research on brain magnetic stimulation in Alzheimer’s, Parkinson’s, and neurodegenerative disorders. 

Dr. Nikkhah-Moshaie and his colleagues demonstrated delivery of magnetoelectric nanoparticles across blood-brain barrier in mice model and reported in Scientific Reports (2016). In 2017, Dr. Nikkhah-Moshaie and his colleagues demonstrated nanoelectroporation of nanoparticles into brain cells (in vitro) under AC magnetic field by FIB and TEM (Scientific Reports).  He received his Bachelor and Master’s degree in Materials Engineering from University of Tehran, Tehran, Iran, 1996-2000 and 2000-2003, respectively. He continued his research with University of Tehran until 2011 when he moved to Florida International University, Miami, FL, USA, to pursue his doctoral studies. He has over 15 years research experience and published numerous research articles in peer-reviewed scientific journals.

Dr. Nikkhah-Moshaie is also an Adjunct Faculty at Department of Mechanical and Materials Engineering, College of Engineering and Computing, FIU, Miami, FL, USA. He is a Senior member of Institute of Electrical and Electronics Engineers (IEEE) in IEEE Magnetics Society and IEEE Engineering in Medicine and Biology Society. He is also a member of Society for Personalized Nanomedicine, Society on NeuroImmune Pharmacology, Society for Brain Mapping and Therapeutics, and Royal Microscopy Society. He has been serving as a reviewer of 11 peer-reviewed scientific journals. Dr. Nikkhah-Moshaie is currently serving as a post-doctoral associate in two federally funded projects by the USA National Institutes of Health (NIH) working on developing nanotechnology techniques for delivery of nanotherapeutics into latently HIV infected brain cells to cure Neuro-AIDS in drug abusers (PI: Prof. Nair). 

Research Area:

  • Nanotechnology, nanomedicine, nanoparticles
  • Non-invasive/ remote targeted drug delivery across blood-brain barrier; in vitro and in vivo
  • Controlled and on-demand drug release into brain cells
  • Neuro-AIDS, neurodegenerative disorders including Alzheimer’s, Parkinson’s, Zika
  • Magnetic stimulation of brain
  • Design and development of novel nanoparticles for biomedical applications, imaging, and drug delivery
  • Characterization and advanced analytical techniques by spectroscopy (AFM, STM), microscopy and microanalysis (TEM, FIB, SEM, EDS, EELS), high-resolution imaging and 3D reconstruction
  • Energy and advanced materials
  • Interrelationship of chemical composition- micro/nanostructure- processing- properties- performance in materials

Recent Publications:

  1. R. Nikkhah-Moshaie, A. Kaushik, R. Sinha, V. Bhardwaj, V. Atluri, R. Dev Jayant, A. Yndart, N. Pala, M. Nair, Nanoelectroporation of magneto-electric nanoparticles as drug nano-carriers into the brain cells, Journal of Neuroimmune Pharmacology, 12 (2017), S66.
  1. R. Nikkhah-Moshaie, A. Kaushik, R. D. Jayant, V. Bhardwaj, M. Nair, TEM Investigation of Nanoparticles Distribution in Mice Brain, Microscopy & Microanalysis, 22 (2016) 1172.
  1. A. Kaushik, R. Nikkhah-Moshaie, R. Sinha, V. Bhardwaj, V. Atluri, R. Dev Jayant, A. Yndart, B. Kateb, N. Pala, M. Nair, Investigation of ac-magnetic field stimulated nanoelectroporation of magneto-electric nano-drug-carrier inside CNS cells, Scientific Reports, 7 (2017) 45663.
  1. A. Kaushik, S. Tiwari, R. D. Jayant, A. Vashist, R. Nikkhah-Moshaie, N. El-Hage, M. Nair, Electrochemical biosensors for early stage Zika diagnostics, Trends in Biotechnology, 2017, Vol. 35, No. 4, 308.
  1. A. Kaushik, R. D. Jayant, R. Nikkhah-Moshaie, V. Bhardwaj, U. Roy, Z. Huang, A. Ruiz, A. Yndart, V. Atluri, N. El-Hage, K. Khalili, M. Nair, Magnetically guided central nervous system delivery and toxicity evaluation of magneto-electric nanocarriers, Scientific Reports, 6 (2016) 25309.
  1. A. D. Raymond, P. Diaz, S. Chevelon, M. Agudelo, A. Yndart-Arias, H. Ding, A. Kaushik, R. Dev Jayant, R. Nikkhah-Moshaie, U. Roy, S. P. Kanthikeel, M. Nair, Microglia-derived HIV Nef+ exosome impairment of the blood–brain barrier is treatable by nanomedicine-based delivery of Nef peptides, Journal of NeuroVirology, 22 (2016) 129.