Office: AHC1 323
Department(s): Cellular Biology and Pharmacology
Dr. Chen received his PH.D degree in Biology from Hunan Normal University, China. His PhD work focus on AtMGT genes encoding Mg2+ transporters in Arabidopsis and its physiological function in plant development. Later, he worked as a Postdoctoral Fellow in Research Center for Eco-Environmental Sciences, CAS, China, in 2009. His work was mainly focused on speciation analysis of arsenic and its metabolism in rice and algae.
Dr. Chen joined in FIU HWCOM in 2010. Currently Dr. Chen is working as a Research Associate in the Laboratory of Dr. Barry P. Rosen. His main focus is to investigate the molecular mechanism of cross-resistance of heavy metals (eg, arsenic, antimony) and antibiotic, biotransformation and transport of environmental organicoarsenicals (eg, roxarsone).
Selected peer-reviewed publications:
- Luis D. Garbinski, Barry P. Rosen and Jian Chen*. Pathways of arsenic uptake and efflux. Environment International 2019, 126: 585-597 (corresponding author)
- Jian Chen, Masafumi Yoshinaga, Barry P. Rosen. The antibiotic action of methylarsenite is an emergent property of microbial communities. Mol Microbiol 2019 111: 487–494
- Jian Chen, Venkadesh Sarkarai Nadar, Barry P. Rosen. A novel MAs(III)-selective ArsR transcriptional repressor. Mol Microbiol. 2017, 106:469-478.
- Jun Zhang, Yan Xu, Tingting Cao, Jian Chen, Barry P. Rosen, Fang-Jie Zhao. Arsenic methylation by a genetically engineered Rhizobium-legume symbiont. Plant Soil. 2017. 416: 259–269
- Jian Chen, Jiaojiao Li, Xuan Jiang, Barry P Rosen. Conserved cysteine residues determine substrate specificity in a novel As(III) S-adenosylmethionine methyltransferase from Aspergillus fumigatus. Mol Microbiol. 2017;104:250-259
- Jian Chen, Barry P. Rosen. Organoarsenical Biotransformations by Shewanella putrefaciens. Environ Sci Technol. 2016, 50:7956-63
- Jian Chen, Masafumi Yoshinaga, Luis D. Garbinski, Barry P. Rosen. Synergistic interaction of glyceraldehydes-3-phosphate dehydrogenase and ArsJ, a novel organoarsenical efflux permease, confers arsenate resistance. Mol Microbiol 2016 100:945-53