Dr. Raymond is dedicated to understanding the mechanisms of HIV pathogenesis and the fight against HIV/AIDS. She developed an interest in HIV in the early 1990's due in part to the great impact on the African-American community. Dr. Raymond completed her graduate training and research in Microbiology & Immunology at Temple University School of Medicine in 2005. She has completed two post doctoral fellowships – University of Pennsylvania/Wistar, Philadelphia, PA and Morehouse School of Medicine, Atlanta, GA. Through her research Dr. Raymond has designed and implemented several studies that directly examine the chronic effects of HIV on immune cell function. While at the Wistar Institute Dr. Raymond started performing translational studies where she used the "bench to bedside" concept to study macrophage responses to HIV-infection in HIV+ subjects directly. She has published over ten peer-reviewed research articles. Dr. Raymond joined Herbert Werthiem College of Medicine in 2012 where she hopes to make significant contributions to research efforts in NeuroAIDS, drug addiction impact on HIV disease, and nanocarrier therapeutics to treat NeuroAIDS within the Department of Immunology.
Education and Training
- PhD, 2005 Microbiology & Immunology, Temple University School of Medicine, Philadelphia, PA
- Master's of Science, Biology, 1999 New York University, New York, NY
- BS, 1991 Massachusetts Institute of Technology, Cambridge, MA
- Post Doctoral Fellowships: (1) Wistar Institute HIV/AIDS Group,University of Pennsylvania School of Medicine, Philadelphia, PA, Florida; (2) Morehouse School of Medicine, Department of Microbiology & Immunology, Atlanta, GA
- Microbiology & Immunology-antiviral innate immunity, macrophage/monocyte biology
- Virology/Neurovirology – HIV/AIDS, NeuroAIDS, and role of HIV Nef protein in viral pathogenesis
- Substance abuse
- Bethsebah Gekonge, Andrea D. Raymond, Xiangfan Yin, Jay Kostman†, Karam Mounzer‡, Ronald G. Collman§, Louise Showe and Luis J. Montaner. Retinoblastoma protein induction by HIV viremia or CCR5 in monocytes exposed to HIV-1 mediates protection from activation-induced apoptosis: ex vivo and in vitro study. J Leukoc Biol. 2012 Aug;92(2):397-405.
- Raymond AD, Campbell-Sims TC, Khan M, Lang M, Huang MB, Bond VC, Powell MD. HIV Type 1 Nef is released from infected cells in CD45(+) microvesicles and is present in the plasma of HIV-infected individuals. AIDS Res Hum Retroviruses. 2011 Feb;27(2):167-78.
- Raymond AD, Gekonge B, Giri MS, Hancock A, Papasavvas E, Chehimi J, Kossenkov AV, Nicols C, Yousef M, Mounzer K, Shull J, Kostman J, Showe L, Montaner LJ. Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia. J Leukoc Biol. 2010 Sep;88(3):589-96.
- Chehimi J, Papasavvas E, Tomescu C, Gekonge B, Abdulhaqq S, Raymond A, Hancock A, Vinekar K,Carty C, Reynolds G, Pistilli M, Mounzer K, Kostman J, Montaner LJ. Inability of plasmacytoid dendritic cells to directly lyse HIV-infected autologous CD4+ T cells despite induction of tumor necrosis factor related apoptosis-inducing ligand. J Virol. 2010 Mar;84(6):2762-73.
- Malavika Giri , Michael Nebozyhn , Andrea Raymond, Bethsebah Gekonge , Aidan Hancock , Shenoa Creer , Calen Nicols , Malik Yousef , Andrea Foulkes , Karam Mounzer , Jane Shull , Guido Silvestri ,Jay Kostman , Ronald Collman , Louise Showe, and Luis J. Montaner. 2009. Circulating monocytes in HIV-1 infected viremic subjects exhibit an antiapoptosis gene signature and virus- and host-mediated apoptosis resistance. Journal of Immunology, 182:4459-4470.
- Raymond AD, Hasham M, Tsygankov AY, Henderson EE. 2007. Herpesvirus saimiri terminal membrane proteins modulate HIV-1 replication by altering Nef and Tat functions. Curr HIV Res. 5(1):79-86.
- Raymond, A.D., Hasham, M.G., Tsygankov, A.Y., and Henderson, E.E. 2006. H. saimiri tyrosinekinase interacting protein inhibits Tat function: a prototypic strategy for restricting HIV-1-induced cytopathic effects in immune cells. Virology 352:253-67.
- Raymond, A.D., Hasham, M.G., Tsygankov, A.Y., and Henderson, E.E. 2004. Herpesvirus saimiriencoded Tip and StpC proteins regulate Human Immunodeficiency Virus 1 replication in T cell lines and primary lymphocytes independently of viral tropism. Virology 324: 60-66.
- Raymond, A.D., Hasham, M.G., Tsygankov, A.Y., and Henderson, E.E. Intracellular Immunization: H saimiri Tip protein inhibits HIV-1 infection in T-lymphocytes. 2003. The FASEB Journal – Immunology 17 (17): C300.
- Palchaudhuri, S., Raymond A., Carlson, E.A., Li, Y., and Zelikoff J.T. Cytotoxic and cytoprotective effects of selenium on bluegill sunfish (Lepomis macrochirus) phagocytic cell in vitro. 2001. Bull Environ Contam Toxicol 67:672-9.
- Zelikoff, J.T., Raymond, A.D., Carlson, E., and Li Yang. 2000. From the ocean to the laboratory: Immunotoxicity in fish. Toxicology Letters 35: 32-36.